Potential anthelmintic and antioxidant activities of Jasminum fruticans L. and its phytochemical analysis

Background: Ethnobotanical investigations conducted in Turkey demonstrated that Jasminum fruticans L. extract and fruit juice had been used against parasites animals. In this study, the possible antihelmintic activity of various J. extracts contributing to its traditional use, was relatively assessed. addition, antioxidant potentials phytochemical composition were investigated since there is a relationship between helminthiasis, oxidative stress phenolic metabolites. Methods: aerial parts subsequently extracted using n-hexane, ethyl acetate (EtOAc) methanol (MeOH). vivo anthelmintic activitiy compared with albendazole as reference adult earthworms. Various methods, including free radical scavenging metal-related assays, assess capacity above-mentioned extracts. Assessment accomplished through total phenolic, acid, flavonoid content assays well liquid chromatography-mass spectrometry (LC-MS/MS) multiple reaction monitoring (MRM) scan modes. Further chlorogenic acid (3-O-caffeoylquinic acid) contents quantified high-performance thin-layer chromatography (HPTLC). Results: Between all tested extracts, MeOH at quantity 50.0 mg/mL, paralysed worms 8.1 min killed them 12.8 min, showing high effect similar albendazole. Similarly, vitro DPPH activity, cupric ion reduction experiments significant activity. screening showed richer regarding Chlorogenic ferulic caffeic gallic only detected extract. Conclusion: Results justify support use medicine an agent. Furthermore, positive correlation found strong along determined